Windows 10 guests will crash periodically with SATA CD/DVD drives on older releases of Fusion. To work around the problem, power off your VM, then go into Virtual Machine> Settings..., and choose CD/DVD (SATA). Then, under Advanced options, change the Bus type from SATA to either SCSI or IDE.
Hopefully that will solve the problem. (I'm going out on a limb and guessing/assuming that this is what the cause is...)
Cheers,
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Darius